Interspecies and in vitro‐in vivo scaling for quantitative modeling of whole‐body drug pharmacokinetics in patients: Application to the anticancer drug oxaliplatin

Quantitative systems pharmacology holds the promises of integrating results from laboratory animals or in vitro human systems into the design of human pharmacokinetic/pharmacodynamic (PK/PD) models allowing for precision and personalized medicine. However, reliable and general in vitro‐to‐in vivo ex...

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Detalles Bibliográficos
Autores principales: Catozzi, Simona, Hill, Roger, Li, Xiao‐Mei, Dulong, Sandrine, Collard, Elodie, Ballesta, Annabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931436/
https://www.ncbi.nlm.nih.gov/pubmed/36537068
http://dx.doi.org/10.1002/psp4.12895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931436/
https://www.ncbi.nlm.nih.gov/pubmed/36537068
http://dx.doi.org/10.1002/psp4.12895

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