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Interspecies and in vitro‐in vivo scaling for quantitative modeling of whole‐body drug pharmacokinetics in patients: Application to the anticancer drug oxaliplatin

Quantitative systems pharmacology holds the promises of integrating results from laboratory animals or in vitro human systems into the design of human pharmacokinetic/pharmacodynamic (PK/PD) models allowing for precision and personalized medicine. However, reliable and general in vitro‐to‐in vivo ex...

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Detalles Bibliográficos
Autores principales:	Catozzi, Simona, Hill, Roger, Li, Xiao‐Mei, Dulong, Sandrine, Collard, Elodie, Ballesta, Annabelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931436/ https://www.ncbi.nlm.nih.gov/pubmed/36537068 http://dx.doi.org/10.1002/psp4.12895

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