Enhancing CRISPR/Cas gene editing through modulating cellular mechanical properties for cancer therapy

Genome editing holds great potential for cancer treatment due to the ability to precisely inactivate or repair cancer-related genes. However, delivery of CRISPR/Cas to solid tumors for efficient cancer therapy remains challenging. Here, we targeted tumor tissue mechanics via a multiplexed dendrimer...

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Detalles Bibliográficos
Autores principales: Zhang, Di, Wang, Guoxun, Yu, Xueliang, Wei, Tuo, Farbiak, Lukas, Johnson, Lindsay T., Taylor, Alan Mark, Xu, Jiazhu, Hong, Yi, Zhu, Hao, Siegwart, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931497/
https://www.ncbi.nlm.nih.gov/pubmed/35551240
http://dx.doi.org/10.1038/s41565-022-01122-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931497/
https://www.ncbi.nlm.nih.gov/pubmed/35551240
http://dx.doi.org/10.1038/s41565-022-01122-3

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