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Enhancing CRISPR/Cas gene editing through modulating cellular mechanical properties for cancer therapy
Genome editing holds great potential for cancer treatment due to the ability to precisely inactivate or repair cancer-related genes. However, delivery of CRISPR/Cas to solid tumors for efficient cancer therapy remains challenging. Here, we targeted tumor tissue mechanics via a multiplexed dendrimer...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931497/ https://www.ncbi.nlm.nih.gov/pubmed/35551240 http://dx.doi.org/10.1038/s41565-022-01122-3 |