ALKBH5‐mediated m(6)A demethylation of TIRAP mRNA promotes radiation‐induced liver fibrosis and decreases radiosensitivity of hepatocellular carcinoma

BACKGROUND: Radiation‐induced hepatic stellate cell (HSC) activation promotes radiation‐induced liver fibrosis (RILF), a complication for hepatocellular carcinoma (HCC) radiotherapy. The demethylase alpha‐ketoglutarate‐dependent dioxygenase alkB homolog 5 (ALKBH5) decreases N6‐methyladenylate methyl...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yuhan, Zhou, Peitao, Deng, Yixun, Cai, Xinni, Sun, Mingrui, Sun, Yining, Wu, Dehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931500/
https://www.ncbi.nlm.nih.gov/pubmed/36792369
http://dx.doi.org/10.1002/ctm2.1198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931500/
https://www.ncbi.nlm.nih.gov/pubmed/36792369
http://dx.doi.org/10.1002/ctm2.1198

Ejemplares similares