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ALKBH5‐mediated m(6)A demethylation of TIRAP mRNA promotes radiation‐induced liver fibrosis and decreases radiosensitivity of hepatocellular carcinoma

BACKGROUND: Radiation‐induced hepatic stellate cell (HSC) activation promotes radiation‐induced liver fibrosis (RILF), a complication for hepatocellular carcinoma (HCC) radiotherapy. The demethylase alpha‐ketoglutarate‐dependent dioxygenase alkB homolog 5 (ALKBH5) decreases N6‐methyladenylate methyl...

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Detalles Bibliográficos
Autores principales:	Chen, Yuhan, Zhou, Peitao, Deng, Yixun, Cai, Xinni, Sun, Mingrui, Sun, Yining, Wu, Dehua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931500/ https://www.ncbi.nlm.nih.gov/pubmed/36792369 http://dx.doi.org/10.1002/ctm2.1198

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