Mostly natural sequencing-by-synthesis for scRNA-seq using Ultima sequencing

Here we introduce a mostly natural sequencing-by-synthesis (mnSBS) method for single-cell RNA sequencing (scRNA-seq), adapted to the Ultima genomics platform, and systematically benchmark it against current scRNA-seq technology. mnSBS uses mostly natural, unmodified nucleotides and only a low fracti...

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Detalles Bibliográficos
Autores principales: Simmons, Sean K., Lithwick-Yanai, Gila, Adiconis, Xian, Oberstrass, Florian, Iremadze, Nika, Geiger-Schuller, Kathryn, Thakore, Pratiksha I., Frangieh, Chris J., Barad, Omer, Almogy, Gilad, Rozenblatt-Rosen, Orit, Regev, Aviv, Lipson, Doron, Levin, Joshua Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931582/
https://www.ncbi.nlm.nih.gov/pubmed/36109685
http://dx.doi.org/10.1038/s41587-022-01452-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931582/
https://www.ncbi.nlm.nih.gov/pubmed/36109685
http://dx.doi.org/10.1038/s41587-022-01452-6

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