Real-time denoising enables high-sensitivity fluorescence time-lapse imaging beyond the shot-noise limit

A fundamental challenge in fluorescence microscopy is the photon shot noise arising from the inevitable stochasticity of photon detection. Noise increases measurement uncertainty and limits imaging resolution, speed and sensitivity. To achieve high-sensitivity fluorescence imaging beyond the shot-no...

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Detalles Bibliográficos
Autores principales: Li, Xinyang, Li, Yixin, Zhou, Yiliang, Wu, Jiamin, Zhao, Zhifeng, Fan, Jiaqi, Deng, Fei, Wu, Zhaofa, Xiao, Guihua, He, Jing, Zhang, Yuanlong, Zhang, Guoxun, Hu, Xiaowan, Chen, Xingye, Zhang, Yi, Qiao, Hui, Xie, Hao, Li, Yulong, Wang, Haoqian, Fang, Lu, Dai, Qionghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931589/
https://www.ncbi.nlm.nih.gov/pubmed/36163547
http://dx.doi.org/10.1038/s41587-022-01450-8

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