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The adapted Activity-By-Contact model for enhancer–gene assignment and its application to single-cell data

MOTIVATION: Identifying regulatory regions in the genome is of great interest for understanding the epigenomic landscape in cells. One fundamental challenge in this context is to find the target genes whose expression is affected by the regulatory regions. A recent successful method is the Activity-...

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Detalles Bibliográficos
Autores principales: Hecker, Dennis, Behjati Ardakani, Fatemeh, Karollus, Alexander, Gagneur, Julien, Schulz, Marcel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931646/
https://www.ncbi.nlm.nih.gov/pubmed/36708003
http://dx.doi.org/10.1093/bioinformatics/btad062