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Application of a physiologically based pharmacokinetic model in predicting captopril disposition in children with chronic kidney disease

Over the last several decades, angiotensin-converting enzyme inhibitors (ACEIs) have been a staple in the treatment of hypertension and renovascular disorders in children. One of the ACEIs, captopril, is projected to have all the benefits of traditional vasodilators. However, conducting clinical tri...

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Detalles Bibliográficos
Autores principales: Khalid, Sundus, Rasool, Muhammad Fawad, Masood, Imran, Imran, Imran, Saeed, Hamid, Ahmad, Tanveer, Alqahtani, Nawaf Shalih, Alshammari, Fahad Ali, Alqahtani, Faleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931704/
https://www.ncbi.nlm.nih.gov/pubmed/36792681
http://dx.doi.org/10.1038/s41598-023-29798-0