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Chemoproteomic discovery of a human RNA ligase

RNA ligases are present across all forms of life. While enzymatic RNA ligation between 5′-PO(4) and 3′-OH termini is prevalent in viruses, fungi, and plants, such RNA ligases are yet to be identified in vertebrates. Here, using a nucleotide-based chemical probe targeting human AMPylated proteome, we...

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Detalles Bibliográficos
Autores principales: Yuan, Yizhi, Stumpf, Florian M., Schlor, Lisa A., Schmidt, Olivia P., Saumer, Philip, Huber, Luisa B., Frese, Matthias, Höllmüller, Eva, Scheffner, Martin, Stengel, Florian, Diederichs, Kay, Marx, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931718/
https://www.ncbi.nlm.nih.gov/pubmed/36792600
http://dx.doi.org/10.1038/s41467-023-36451-x