Combining non-negative matrix factorization with graph Laplacian regularization for predicting drug-miRNA associations based on multi-source information fusion

Increasing evidences suggest that miRNAs play a key role in the occurrence and progression of many complex human diseases. Therefore, targeting dysregulated miRNAs with small molecule drugs in the clinical has become a new treatment. Nevertheless, it is high cost and time-consuming for identifying m...

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Detalles Bibliográficos
Autores principales: Wang, Mei-Neng, Li, Yu, Lei, Li-Lan, Ding, De-Wu, Xie, Xue-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931722/
https://www.ncbi.nlm.nih.gov/pubmed/36817132
http://dx.doi.org/10.3389/fphar.2023.1132012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931722/
https://www.ncbi.nlm.nih.gov/pubmed/36817132
http://dx.doi.org/10.3389/fphar.2023.1132012

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