Human iPSC-derived preclinical models to identify toxicity of tumor-specific T cells with clinical potential

The balance between safety and efficacy of T cell therapies remains challenging and T cell mediated toxicities have occurred. The stringent selection of tumor-specific targets and careful selection of tumor-specific T cells using T cell toxicity screenings are essential. In vitro screening options a...

Descripción completa

Detalles Bibliográficos
Autores principales: van Amerongen, Rosa A., Morton, Laura T., Chaudhari, Umesh G., Remst, Dennis F.G., Hagedoorn, Renate S., van den Berg, Cathelijne W., Freund, Christian, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931760/
https://www.ncbi.nlm.nih.gov/pubmed/36816758
http://dx.doi.org/10.1016/j.omtm.2023.01.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931760/
https://www.ncbi.nlm.nih.gov/pubmed/36816758
http://dx.doi.org/10.1016/j.omtm.2023.01.005

Ejemplares similares