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Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya

Asgard archaea include the closest known archaeal relatives of eukaryotes. Here, we investigate the evolution and function of Asgard thymidylate synthases and other folate-dependent enzymes required for the biosynthesis of DNA, RNA, amino acids and vitamins, as well as syntrophic amino acid utilizat...

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Detalles Bibliográficos
Autores principales: Filée, Jonathan, Becker, Hubert F., Mellottee, Lucille, Eddine, Rima Zein, Li, Zhihui, Yin, Wenlu, Lambry, Jean-Christophe, Liebl, Ursula, Myllykallio, Hannu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931769/
https://www.ncbi.nlm.nih.gov/pubmed/36792581
http://dx.doi.org/10.1038/s41467-023-36487-z