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MicroRNA-profiling of miR-371~373- and miR-302/367-clusters in serum and cerebrospinal fluid identify patients with intracranial germ cell tumors

PURPOSE: Intracranial germ cell tumors (iGCT) comprise germinoma and non-germinoma. Their diagnosis predominantly relies on biopsy as only one-fifth of patients present with elevated biomarkers (AFP/ß-HCG) in serum or cerebrospinal fluid (CSF). MicroRNAs (miR/miRNA) have emerged as non-invasive biom...

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Detalles Bibliográficos
Autores principales: Schönberger, Stefan, Mohseni, Mahsa Mir, Ellinger, Jörg, Tran, Giao Vu Quynh, Becker, Martina, Claviez, Alexander, Classen, Carl-Friedrich, Hermes, Barbara, Driever, Pablo Hernáiz, Jorch, Norbert, Lauten, Melchior, Mehlitz, Marcus, Schäfer, Niklas, Scheer-Preiss, Johanna, Schneider, Dominik T., Troeger, Anja, Calaminus, Gabriele, Dilloo, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931786/
https://www.ncbi.nlm.nih.gov/pubmed/35171328
http://dx.doi.org/10.1007/s00432-022-03915-4