IL-17A expression by both T cells and non-T cells contribute to HSV-IL-2-induced CNS demyelination

Previously we reported that a recombinant HSV-1 expressing murine IL-2 (HSV-IL-2) causes CNS demyelination in different strains of mice and in a T cell-dependent manner. Since T(H)17 cells have been implicated in CNS pathology, in the present study, we looked into the effects of IL-17A(-/-) and thre...

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Detalles Bibliográficos
Autores principales: Hirose, Satoshi, Wang, Shaohui, Jaggi, Ujjaldeep, Matundan, Harry H., Kato, Mihoko, Song, Xue-Ying, Molesworth-Kenyon, Sara J., Lausch, Robert N., Ghiasi, Homayon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931899/
https://www.ncbi.nlm.nih.gov/pubmed/36817487
http://dx.doi.org/10.3389/fimmu.2023.1102486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931899/
https://www.ncbi.nlm.nih.gov/pubmed/36817487
http://dx.doi.org/10.3389/fimmu.2023.1102486

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