Cargando…

IL-17A expression by both T cells and non-T cells contribute to HSV-IL-2-induced CNS demyelination

Previously we reported that a recombinant HSV-1 expressing murine IL-2 (HSV-IL-2) causes CNS demyelination in different strains of mice and in a T cell-dependent manner. Since T(H)17 cells have been implicated in CNS pathology, in the present study, we looked into the effects of IL-17A(-/-) and thre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hirose, Satoshi, Wang, Shaohui, Jaggi, Ujjaldeep, Matundan, Harry H., Kato, Mihoko, Song, Xue-Ying, Molesworth-Kenyon, Sara J., Lausch, Robert N., Ghiasi, Homayon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931899/ https://www.ncbi.nlm.nih.gov/pubmed/36817487 http://dx.doi.org/10.3389/fimmu.2023.1102486

Ejemplares similares

Type 2 Innate Lymphoid Cells Induce CNS Demyelination in an HSV-IL-2 Mouse Model of Multiple Sclerosis
por: Hirose, Satoshi, et al.
Publicado: (2020)

Loss of ICP22 in HSV-1 Elicits Immune Infiltration and Maintains Stromal Keratitis Despite Reduced Primary and Latent Virus Infectivity
por: Matundan, Harry H., et al.
Publicado: (2019)

Protocol for a mouse CNS demyelination model induced by a combination of HSV-1 and IL-2
por: Hirose, Satoshi, et al.
Publicado: (2021)

Role of Herpes Simplex Virus Type 1 (HSV-1) Glycoprotein K (gK) Pathogenic CD8(+) T Cells in Exacerbation of Eye Disease
por: Jaggi, Ujjaldeep, et al.
Publicado: (2018)

Herpes Simplex Virus 1 Glycoproteins Differentially Regulate the Activity of Costimulatory Molecules and T Cells
por: Matundan, Harry H., et al.
Publicado: (2022)

Essential role of M1 macrophages in blocking cytokine storm and pathology associated with murine HSV-1 infection
por: Jaggi, Ujjaldeep, et al.
Publicado: (2021)

Knockout of signal peptide peptidase in the eye reduces HSV-1 replication and eye disease in ocularly infected mice
por: Wang, Shaohui, et al.
Publicado: (2022)

Suppression of CD80 Expression by ICP22 Affects Herpes Simplex Virus Type 1 Replication and CD8(+)IFN-γ(+) Infiltrates in the Eyes of Infected Mice but Not Latency Reactivation
por: Matundan, Harry H., et al.
Publicado: (2021)

Increased phagocytosis in the presence of enhanced M2-like macrophage responses correlates with increased primary and latent HSV-1 infection
por: Jaggi, Ujjaldeep, et al.
Publicado: (2020)

Absence of signal peptide peptidase in peripheral sensory neurons affects latency-reactivation in HSV-1 ocularly infected mice
por: Wang, Shaohui, et al.
Publicado: (2022)

Blocking HSV-1 glycoprotein K binding to signal peptide peptidase reduces virus infectivity in vitro and in vivo
por: Wang, Shaohui, et al.
Publicado: (2021)

IL-2 Suppression of IL-12p70 by a Recombinant HSV-1 Expressing IL-2 Induces T-Cell Auto-Reactivity and CNS Demyelination
por: Zandian, Mandana, et al.
Publicado: (2011)

Binding of herpesvirus entry mediator (HVEM) and HSV-1 gD affect reactivation but not latency levels
por: Jaggi, Ujjaldeep, et al.
Publicado: (2023)

Role of T(H)17 Responses in Increasing Herpetic Keratitis in the Eyes of Mice Infected with HSV-1
por: Hirose, Satoshi, et al.
Publicado: (2020)

Use of cytokine immunotherapy to block CNS demyelination induced by a recombinant HSV-1 expressing IL-2
por: Zandian, Mandana, et al.
Publicado: (2011)

Suppression of IL-12p70 formation by IL-2 or following macrophage depletion causes T-cell autoreactivity leading to CNS demyelination in HSV-1-infected mice
por: Lee, Dhong Hyun, et al.
Publicado: (2017)

Absence of CD28-CTLA4-PD-L1 Costimulatory Molecules Reduces Herpes Simplex Virus 1 Reactivation
por: Matundan, Harry H., et al.
Publicado: (2021)

CCR2(+) migratory macrophages with M1 status are the early-responders in the cornea of HSV-1 infected mice
por: Lee, Dhong Hyun, et al.
Publicado: (2019)

Correction for Hirose et al., “Impact of a Demyelination-Inducing Central Nervous System Virus on Expression of Demyelination Genes in Type 2 Lymphoid Cells”
por: Hirose, Satoshi, et al.
Publicado: (2021)

Ocular infection of mice with an avirulent recombinant HSV-1 expressing IL-4 and an attenuated HSV-1 strain generates virulent recombinants in vivo
por: Mott, Kevin R., et al.
Publicado: (2010)

Stacking the odds: Multiple sites for HSV-1 latency
por: Wang, Shaohui, et al.
Publicado: (2023)

Resident Corneal Cells Communicate with Neutrophils Leading to the Production of IP-10 during the Primary Inflammatory Response to HSV-1 Infection
por: Molesworth-Kenyon, S. J., et al.
Publicado: (2012)

IL-1 signal affects both protection and pathogenesis of virus-induced chronic CNS demyelinating disease
por: Kim, Byung S, et al.
Publicado: (2012)

Role of IL-18 induced Amphiregulin expression on virus induced ocular lesions
por: Varanasi, Siva Karthik, et al.
Publicado: (2018)

Involvement of STAT4 in IgG subtype switching and ocular HSV-1 replication in mice
por: Allen, Sariah J., et al.
Publicado: (2010)

A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages
por: Mott, Kevin R, et al.
Publicado: (2009)

A comparative study of experimental mouse models of central nervous system demyelination
por: Dumitrascu, Oana M., et al.
Publicado: (2014)

Roles of regulatory T cells and IL-10 in virus-induced demyelination
por: Perlman, Stanley, et al.
Publicado: (2017)

CD8α Dendritic Cells Drive Establishment of HSV-1 Latency
por: Mott, Kevin R., et al.
Publicado: (2014)

HSV-1 Modulates IL-6 Receptor Expression on Human Dendritic Cells
por: Birzer, Alexandra, et al.
Publicado: (2020)

HSV-1 and Endogenous Retroviruses as Risk Factors in Demyelination
por: Bello-Morales, Raquel, et al.
Publicado: (2021)

Case Report: Anti-NMDAR Encephalitis With Anti-MOG CNS Demyelination After Recurrent CNS Demyelination
por: Ren, Bing-Yan, et al.
Publicado: (2021)

Contrasting effects of immunosuppression on herpes simplex virus type I (HSV I) induced central nervous system (CNS) demyelination in mice
por: Kastrukoff, Lorne F., et al.
Publicado: (1993)

Curing glioblastoma: oncolytic HSV-IL12 and checkpoint blockade
por: Saha, Dipongkor, et al.
Publicado: (2017)

CNS Demyelination with TNF-α Blockers
por: Kemanetzoglou, Elissavet, et al.
Publicado: (2017)

IL-3 Is a Marker of Encephalitogenic T Cells, but Not Essential for CNS Autoimmunity
por: Lee, Priscilla W., et al.
Publicado: (2018)

HSV-1 miR-H6 Inhibits HSV-1 Replication and IL-6 Expression in Human Corneal Epithelial Cells In Vitro
por: Duan, Fang, et al.
Publicado: (2012)

The Role of Peripheral CNS-Directed Antibodies in Promoting Inflammatory CNS Demyelination
por: Kinzel, Silke, et al.
Publicado: (2017)

Binding of HSV-1 Glycoprotein K (gK) to Signal Peptide Peptidase (SPP) Is Required for Virus Infectivity
por: Allen, Sariah J., et al.
Publicado: (2014)

Deciphering the Footprints of Autoimmunity in CNS Demyelinating Disorders
por: Netravathi, M
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rin5uv0fek73a376p8h2eit9jm