Conjugation to a cell-penetrating peptide drives the tumour accumulation of the GLP1R antagonist exendin(9-39)

PURPOSE: Exendin, an analogue of the glucagon-like peptide 1 (GLP1), is an excellent tracer for molecular imaging of pancreatic beta cells and beta cell-derived tumours. The commonly used form, exendin-4, activates the GLP1 receptor and causes internalisation of the peptide-receptor complex. As a co...

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Detalles Bibliográficos
Autores principales: Collado Camps, Estel, van Lith, Sanne A. M., Kip, Annemarie, Frielink, Cathelijne, Joosten, Lieke, Brock, Roland, Gotthardt, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931918/
https://www.ncbi.nlm.nih.gov/pubmed/36446951
http://dx.doi.org/10.1007/s00259-022-06041-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931918/
https://www.ncbi.nlm.nih.gov/pubmed/36446951
http://dx.doi.org/10.1007/s00259-022-06041-y

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