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Polygenic Risk Scores and the Need for Pharmacotherapy in Neonatal Abstinence Syndrome
OBJECTIVES: To identify genetic variants associated with NAS through a Genome Wide Association Study (GWAS) and estimate a Polygenic Risk Score (PRS) model for NAS. DESIGN: A prospective case-control study included 476 in-utero opioid-exposed term neonates. A GWAS of 1000 Genomes-imputed genotypes w...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931940/ https://www.ncbi.nlm.nih.gov/pubmed/35974158 http://dx.doi.org/10.1038/s41390-022-02243-0 |