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Nusinersen mitigates neuroinflammation in severe spinal muscular atrophy patients

BACKGROUND: Neuroinflammation contributes to the onset and progression of neurodegenerative diseases, but has not been specifically investigated in patients affected by severe and milder forms of spinal muscular atrophy (SMA). METHODS: In this two-center retrospective study, we investigated signatur...

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Detalles Bibliográficos
Autores principales: Nuzzo, Tommaso, Russo, Rosita, Errico, Francesco, D’Amico, Adele, Tewelde, Awet G., Valletta, Mariangela, Hassan, Amber, Tosi, Michele, Panicucci, Chiara, Bruno, Claudio, Bertini, Enrico, Chambery, Angela, Pellizzoni, Livio, Usiello, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932014/
https://www.ncbi.nlm.nih.gov/pubmed/36792810
http://dx.doi.org/10.1038/s43856-023-00256-2