Cargando…
Nusinersen mitigates neuroinflammation in severe spinal muscular atrophy patients
BACKGROUND: Neuroinflammation contributes to the onset and progression of neurodegenerative diseases, but has not been specifically investigated in patients affected by severe and milder forms of spinal muscular atrophy (SMA). METHODS: In this two-center retrospective study, we investigated signatur...
Autores principales: | Nuzzo, Tommaso, Russo, Rosita, Errico, Francesco, D’Amico, Adele, Tewelde, Awet G., Valletta, Mariangela, Hassan, Amber, Tosi, Michele, Panicucci, Chiara, Bruno, Claudio, Bertini, Enrico, Chambery, Angela, Pellizzoni, Livio, Usiello, Alessandro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932014/ https://www.ncbi.nlm.nih.gov/pubmed/36792810 http://dx.doi.org/10.1038/s43856-023-00256-2 |
Ejemplares similares
-
Nusinersen Induces Disease-Severity-Specific Neurometabolic Effects in Spinal Muscular Atrophy
por: Errico, Francesco, et al.
Publicado: (2022) -
Nusinersen for spinal muscular atrophy
por: Wurster, Claudia D., et al.
Publicado: (2018) -
Spinal muscular atrophy
por: D'Amico, Adele, et al.
Publicado: (2011) -
Nusinersen in pediatric and adult patients with type III spinal muscular atrophy
por: Pera, Maria Carmela, et al.
Publicado: (2021) -
SMN deficiency perturbs monoamine neurotransmitter metabolism in spinal muscular atrophy
por: Valsecchi, Valeria, et al.
Publicado: (2023)