After virus exposure, early bystander naïve CD8 T cell activation relies on NAD(+) salvage metabolism

CD8 T cells play a central role in antiviral immunity. Type I interferons are among the earliest responders after virus exposure and can cause extensive reprogramming and antigen-independent bystander activation of CD8 T cells. Although bystander activation of pre-existing memory CD8 T cells is know...

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Detalles Bibliográficos
Autores principales: Holay, Namit, Kennedy, Barry E., Murphy, J. Patrick, Konda, Prathyusha, Giacomantonio, Michael, Brauer-Chapin, Tatjana, Paulo, Joao A., Kumar, Vishnupriyan, Kim, Youra, Elaghil, Mariam, Sisson, Gary, Clements, Derek, Richardson, Christopher, Gygi, Steven P., Gujar, Shashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932030/
https://www.ncbi.nlm.nih.gov/pubmed/36818473
http://dx.doi.org/10.3389/fimmu.2022.1047661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932030/
https://www.ncbi.nlm.nih.gov/pubmed/36818473
http://dx.doi.org/10.3389/fimmu.2022.1047661

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