Mechanical injury accentuates lipid deposition in ApoE(–/–) mice and advance aortic valve stenosis: A novel modified aortic valve stenosis model

BACKGROUND: Current mouse models still have limitations in studying aortic valve stenosis (AVS). A suitable animal model bearing a close resemblance to the pathophysiological processes of humans needs to be developed. Here, we combined two risk factors to create a mouse model that mimics the patholo...

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Detalles Bibliográficos
Autores principales: Wen, Dezhong, Hu, Li, Shan, Jianggui, Zhang, Hengyuan, Hu, Liuhua, Yuan, Ancai, Pu, Jun, Xue, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932047/
https://www.ncbi.nlm.nih.gov/pubmed/36818346
http://dx.doi.org/10.3389/fcvm.2023.1119746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932047/
https://www.ncbi.nlm.nih.gov/pubmed/36818346
http://dx.doi.org/10.3389/fcvm.2023.1119746

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