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Developmental programming: adverse sexually dimorphic transcriptional programming of gestational testosterone excess in cardiac left ventricle of fetal sheep
Adverse in-utero insults during fetal life alters offspring’s developmental trajectory, including that of the cardiovascular system. Gestational hyperandrogenism is once such adverse in-utero insult. Gestational testosterone (T)-treatment, an environment of gestational hyperandrogenism, manifests as...
Autores principales: | Ramamoorthi Elangovan, Venkateswaran, Saadat, Nadia, Ghnenis, Adel, Padmanabhan, Vasantha, Vyas, Arpita K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932081/ https://www.ncbi.nlm.nih.gov/pubmed/36792653 http://dx.doi.org/10.1038/s41598-023-29212-9 |
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