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Anti-DEspR antibody treatment improves survival and reduces neurologic deficits in a hypertensive, spontaneous intracerebral hemorrhage (hsICH) rat model

Progressive secondary brain injury—induced by dysregulated neuroinflammation in spontaneous intracerebral hemorrhage (sICH)—underlies high sICH-mortality and remains without FDA-approved pharmacotherapy. Clinical insight that hematoma-directed interventions do not improve mortality prioritizes resol...

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Detalles Bibliográficos
Autores principales: Herrera, Victoria L. M., Gromisch, Christopher M., Decano, Julius L., Pasion, Khristine Amber, Tan, Glaiza L. A., Hua, Ning, Takahashi, Courtney E., Greer, David M., Ruiz-Opazo, Nelson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932093/
https://www.ncbi.nlm.nih.gov/pubmed/36792616
http://dx.doi.org/10.1038/s41598-023-28149-3