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Anti-DEspR antibody treatment improves survival and reduces neurologic deficits in a hypertensive, spontaneous intracerebral hemorrhage (hsICH) rat model
Progressive secondary brain injury—induced by dysregulated neuroinflammation in spontaneous intracerebral hemorrhage (sICH)—underlies high sICH-mortality and remains without FDA-approved pharmacotherapy. Clinical insight that hematoma-directed interventions do not improve mortality prioritizes resol...
Autores principales: | Herrera, Victoria L. M., Gromisch, Christopher M., Decano, Julius L., Pasion, Khristine Amber, Tan, Glaiza L. A., Hua, Ning, Takahashi, Courtney E., Greer, David M., Ruiz-Opazo, Nelson |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932093/ https://www.ncbi.nlm.nih.gov/pubmed/36792616 http://dx.doi.org/10.1038/s41598-023-28149-3 |
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