Cargando…

SVEP1 is an endogenous ligand for the orphan receptor PEAR1

Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (SVEP1) is an extracellular matrix protein that causally promotes vascular disease and associates with platelet reactivity in humans. Here, using a human genomic and proteomic approach, we identify a high affinity, disease-re...

Descripción completa

Detalles Bibliográficos
Autores principales: Elenbaas, Jared S., Pudupakkam, Upasana, Ashworth, Katrina J., Kang, Chul Joo, Patel, Ved, Santana, Katherine, Jung, In-Hyuk, Lee, Paul C., Burks, Kendall H., Amrute, Junedh M., Mecham, Robert P., Halabi, Carmen M., Alisio, Arturo, Di Paola, Jorge, Stitziel, Nathan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932102/
https://www.ncbi.nlm.nih.gov/pubmed/36792666
http://dx.doi.org/10.1038/s41467-023-36486-0