The impact of glucose on mitochondria and life span is determined by the integrity of proline catabolism in Caenorhabditis elegans

Mutations in genes involved in mitochondrial proline catabolism lead to the rare genetic disorder hyperprolinemia in humans. We have previously reported that mutations of proline catabolic genes in Caenorhabditis elegans impair mitochondrial homeostasis and shorten life span, and that these effects...

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Detalles Bibliográficos
Autores principales: Feng, Xi, Wang, Xinyu, Zhou, Lei, Pang, Shanshan, Tang, Haiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
JBC Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932108/
https://www.ncbi.nlm.nih.gov/pubmed/36626986
http://dx.doi.org/10.1016/j.jbc.2023.102881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932108/
https://www.ncbi.nlm.nih.gov/pubmed/36626986
http://dx.doi.org/10.1016/j.jbc.2023.102881

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