Inhibition of RIPK1 kinase does not affect diabetes development: β-Cells survive RIPK1 activation

OBJECTIVES: Type 1 diabetes (T1D) is caused by progressive immune-mediated loss of insulin-producing β-cells. Inflammation is detrimental to β-cell function and survival, moreover, both apoptosis and necrosis have been implicated as mechanisms of F062-cell loss in T1D. The receptor interacting serin...

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Detalles Bibliográficos
Autores principales: Takiishi, Tatiana, Xiao, Peng, Franchimont, Marie, Gilglioni, Eduardo H., Arroba, Erick N., Gurzov, Esteban N., Bertrand, Mathieu JM., Cardozo, Alessandra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932129/
https://www.ncbi.nlm.nih.gov/pubmed/36707047
http://dx.doi.org/10.1016/j.molmet.2023.101681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932129/
https://www.ncbi.nlm.nih.gov/pubmed/36707047
http://dx.doi.org/10.1016/j.molmet.2023.101681

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