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A straightforward method to quantify circulating mRNAs as biomarkers of colorectal cancer

Optimizing the biomarker combination to be analyzed in liquid biopsies should improve personalized medicine. We developed a method to purify circulating cell-free mRNAs from plasma samples and to quantify them by RT-qPCR. We selected three candidate colorectal cancer biomarkers (B2M, TIMP-1, and CLU...

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Detalles Bibliográficos
Autores principales: Grosgeorges, Marie, Picque Lasorsa, Laurence, Pastor, Brice, Prévostel, Corinne, Crapez, Evelyne, Sanchez, Cynthia, Frayssinoux, Florence, Jarlier, Marta, Pezzella, Véronique, Monard, Laure, Ychou, Marc, Thierry, Alain R., Mazard, Thibault, Blache, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932139/
https://www.ncbi.nlm.nih.gov/pubmed/36792801
http://dx.doi.org/10.1038/s41598-023-29948-4