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The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis

CircRNAs play crucial roles in various malignancies via an increasing number of reported regulatory mechanisms, including the classic sponging mechanism between circRNAs and micro RNAs (miRNAs). We performed bioinformatic analyses and identified circTLK1 as a regulator of malignant chordoma progress...

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Detalles Bibliográficos
Autores principales: Lou, Jingbing, Zhang, Hongliang, Huang, Qingshan, Chen, Chenglong, Wang, Wei, Niu, Jianfang, Xu, Jiuhui, Ren, Tingting, Huang, Yi, Tang, Xiaodong, Guo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932141/
https://www.ncbi.nlm.nih.gov/pubmed/36792585
http://dx.doi.org/10.1038/s41420-023-01332-1