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The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis
CircRNAs play crucial roles in various malignancies via an increasing number of reported regulatory mechanisms, including the classic sponging mechanism between circRNAs and micro RNAs (miRNAs). We performed bioinformatic analyses and identified circTLK1 as a regulator of malignant chordoma progress...
Autores principales: | Lou, Jingbing, Zhang, Hongliang, Huang, Qingshan, Chen, Chenglong, Wang, Wei, Niu, Jianfang, Xu, Jiuhui, Ren, Tingting, Huang, Yi, Tang, Xiaodong, Guo, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932141/ https://www.ncbi.nlm.nih.gov/pubmed/36792585 http://dx.doi.org/10.1038/s41420-023-01332-1 |
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