Molecular mechanisms of coronary artery disease risk at the PDGFD locus

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Genome wide association studies for coronary artery disease (CAD) have identified a risk locus at 11q22.3. Here, we verify with mechanistic studies that rs2019090 and PDGFD represent the functional variant and gene at this locus. Further, FOXC1/C2 transcription factor binding at rs2019090 is shown t...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Jung, Cheng, Paul, Travisano, Stanislao, Weldy, Chad, Monteiro, João P., Kundu, Ramendra, Nguyen, Trieu, Sharma, Disha, Shi, Huitong, Lin, Yi, Liu, Boxiang, Haldar, Saptarsi, Jackson, Simon, Quertermous, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932166/
https://www.ncbi.nlm.nih.gov/pubmed/36792607
http://dx.doi.org/10.1038/s41467-023-36518-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932166/
https://www.ncbi.nlm.nih.gov/pubmed/36792607
http://dx.doi.org/10.1038/s41467-023-36518-9

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