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Nsun2 coupling with RoRγt shapes the fate of Th17 cells and promotes colitis

T helper 17 (Th17) cells are a subset of CD4(+) T helper cells involved in the inflammatory response in autoimmunity. Th17 cells secrete Th17 specific cytokines, such as IL-17A and IL17-F, which are governed by the master transcription factor RoRγt. However, the epigenetic mechanism regulating Th17...

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Detalles Bibliográficos
Autores principales: Yang, Wen-Lan, Qiu, Weinan, Zhang, Ting, Xu, Kai, Gu, Zi-Juan, Zhou, Yu, Xu, Heng-Ji, Yang, Zhong-Zhou, Shen, Bin, Zhao, Yong-Liang, Zhou, Qi, Yang, Ying, Li, Wei, Yang, Peng-Yuan, Yang, Yun-Gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932167/
https://www.ncbi.nlm.nih.gov/pubmed/36792629
http://dx.doi.org/10.1038/s41467-023-36595-w