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Nsun2 coupling with RoRγt shapes the fate of Th17 cells and promotes colitis
T helper 17 (Th17) cells are a subset of CD4(+) T helper cells involved in the inflammatory response in autoimmunity. Th17 cells secrete Th17 specific cytokines, such as IL-17A and IL17-F, which are governed by the master transcription factor RoRγt. However, the epigenetic mechanism regulating Th17...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932167/ https://www.ncbi.nlm.nih.gov/pubmed/36792629 http://dx.doi.org/10.1038/s41467-023-36595-w |