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Genome-scale CRISPR-Cas9 knockout screening in nasopharyngeal carcinoma for radiosensitive and radioresistant genes

BACKGROUND: Genome-scale CRISPR-Cas9 knockout screening may provide new insights into the mechanism underlying clinical radioresistance in nasopharyngeal carcinoma (NPC), which is remain largely unknown. Our objective was to screen the functional genes associated with radiosensitivity and radioresis...

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Detalles Bibliográficos
Autores principales: Zhou, Ziyan, Chen, Gang, Shen, Mingjun, Li, Jixi, Liu, Kang, Liu, Ming, Shi, Shuo, Yang, Dong, Chen, Wei, Chen, Sixia, Yin, Yuanxiu, Qin, Yating, Su, Xuejin, Chen, Weimin, Kang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932185/
https://www.ncbi.nlm.nih.gov/pubmed/36739730
http://dx.doi.org/10.1016/j.tranon.2023.101625