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Nicotine alleviates MPTP-induced nigrostriatal damage through modulation of JNK and ERK signaling pathways in the mice model of Parkinson’s disease

Introduction: Nicotine (Nic) has previously been proven to reduce neurodegeneration in the models of Parkinson’s disease (PD). The present study is intended to investigate the detailed mechanisms related to the potential neuroprotective effects of Nic in vivo. Methods: We established a PD model usin...

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Detalles Bibliográficos
Autores principales: Ruan, Sisi, Xie, Jiqing, Wang, Linhai, Guo, Lulu, Li, Yan, Fan, Wu, Ji, Rongzhan, Gong, Zhenlin, Xu, Yan, Mao, Jian, Xie, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932206/
https://www.ncbi.nlm.nih.gov/pubmed/36817162
http://dx.doi.org/10.3389/fphar.2023.1088957