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Modulating the activity of human nociceptors with a SCN10A promoter-specific viral vector tool

Despite the high prevalence of chronic pain as a disease in our society, there is a lack of effective treatment options for patients living with this condition. Gene therapies using recombinant AAVs are a direct method to selectively express genes of interest in target cells with the potential of, i...

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Detalles Bibliográficos
Autores principales: Mouchbahani-Constance, Stephanie, Lagard, Camille, Schweizer, Justine, Labonté, Isabelle, Georgiopoulos, Miltiadis, Otis, Colombe, St-Louis, Manon, Troncy, Eric, Sarret, Philippe, Ribeiro-Da-Silva, Alfredo, Ouellet, Jean A., Séguéla, Philippe, Paquet, Marie-Eve, Sharif-Naeini, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932673/
https://www.ncbi.nlm.nih.gov/pubmed/36816616
http://dx.doi.org/10.1016/j.ynpai.2023.100120