Cargando…

Serum opacity factor rescues fertility among female Scarb1(−/−) mice by reducing HDL-free cholesterol bioavailability

Human female infertility, 20% of which is idiopathic, is a public health problem for which better diagnostics and therapeutics are needed. A novel cause of infertility emerged from studies of female mice deficient in the HDL receptor gene (Scarb1). These mice are infertile and have high plasma HDL c...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosales, Corina, Yelamanchili, Dedipya, Gillard, Baiba K., Liu, Jing, Gotto, Antonio M., Pownall, Henry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932678/
https://www.ncbi.nlm.nih.gov/pubmed/36596339
http://dx.doi.org/10.1016/j.jlr.2022.100327