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Serum opacity factor rescues fertility among female Scarb1(−/−) mice by reducing HDL-free cholesterol bioavailability

Human female infertility, 20% of which is idiopathic, is a public health problem for which better diagnostics and therapeutics are needed. A novel cause of infertility emerged from studies of female mice deficient in the HDL receptor gene (Scarb1). These mice are infertile and have high plasma HDL c...

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Detalles Bibliográficos
Autores principales: Rosales, Corina, Yelamanchili, Dedipya, Gillard, Baiba K., Liu, Jing, Gotto, Antonio M., Pownall, Henry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932678/
https://www.ncbi.nlm.nih.gov/pubmed/36596339
http://dx.doi.org/10.1016/j.jlr.2022.100327

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