Genetic adaptation to pathogens and increased risk of inflammatory disorders in post-Neolithic Europe

Ancient genomics can directly detect human genetic adaptation to environmental cues. However, it remains unclear how pathogens have exerted selective pressures on human genome diversity across different epochs and affected present-day inflammatory disease risk. Here, we use an ancestry-aware approxi...

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Detalles Bibliográficos
Autores principales: Kerner, Gaspard, Neehus, Anna-Lena, Philippot, Quentin, Bohlen, Jonathan, Rinchai, Darawan, Kerrouche, Nacim, Puel, Anne, Zhang, Shen-Ying, Boisson-Dupuis, Stéphanie, Abel, Laurent, Casanova, Jean-Laurent, Patin, Etienne, Laval, Guillaume, Quintana-Murci, Lluis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932995/
https://www.ncbi.nlm.nih.gov/pubmed/36819665
http://dx.doi.org/10.1016/j.xgen.2022.100248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9932995/
https://www.ncbi.nlm.nih.gov/pubmed/36819665
http://dx.doi.org/10.1016/j.xgen.2022.100248

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