Development of a Universal Second-Tier Newborn Screening LC–MS/MS Method for Amino Acids, Lysophosphatidylcholines, and Organic Acids

[Image: see text] First-tier MS-based newborn screening by flow injection analysis can have high presumptive positive rates, often due to isomeric/isobaric compounds or poor biomarker specificity. These presumptive positive samples can be analyzed by second-tier screening assays employing separation...

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Detalles Bibliográficos
Autores principales: Kilgore, Matthew B., Platis, Dimitrios, Lim, Timothy, Isenberg, Samantha, Pickens, C. Austin, Cuthbert, Carla, Petritis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933048/
https://www.ncbi.nlm.nih.gov/pubmed/36724346
http://dx.doi.org/10.1021/acs.analchem.2c03098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933048/
https://www.ncbi.nlm.nih.gov/pubmed/36724346
http://dx.doi.org/10.1021/acs.analchem.2c03098

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