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Roadmap for understanding mechanisms on how Epstein–Barr virus triggers multiple sclerosis and for translating these discoveries in clinical trials

Here, we offer a roadmap for what might be studied next in understanding how EBV triggers MS. We focus on two areas: The first area concerns the molecular mechanisms underlying how clonal antibody in the CSF emanates in widespread molecular mimicry to key antigens in the nervous system including Gli...

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Detalles Bibliográficos
Autores principales: Lanz, Tobias V, Robinson, William H, Ho, Peggy P, Steinman, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933111/
https://www.ncbi.nlm.nih.gov/pubmed/36815946
http://dx.doi.org/10.1002/cti2.1438