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Evolution of nanobodies specific for BCL11A
Transcription factors (TFs) control numerous genes that are directly relevant to many human disorders. However, developing specific reagents targeting TFs within intact cells is challenging due to the presence of highly disordered regions within these proteins. Intracellular antibodies offer opportu...
Autores principales: | Yin, Maolu, Izadi, Manizheh, Tenglin, Karin, Viennet, Thibault, Zhai, Liting, Zheng, Ge, Arthanari, Haribabu, Dassama, Laura M. K., Orkin, Stuart H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933118/ https://www.ncbi.nlm.nih.gov/pubmed/36626555 http://dx.doi.org/10.1073/pnas.2218959120 |
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