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Taxonomy of fibroblasts and progenitors in the synovial joint at single-cell resolution

OBJECTIVES: Fibroblasts in synovium include fibroblast-like synoviocytes (FLS) in the lining and Thy1+ connective-tissue fibroblasts in the sublining. We aimed to investigate their developmental origin and relationship with adult progenitors. METHODS: To discriminate between Gdf5-lineage cells deriv...

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Detalles Bibliográficos
Autores principales: Collins, Fraser L, Roelofs, Anke J, Symons, Rebecca A, Kania, Karolina, Campbell, Ewan, Collie-duguid, Elaina S R, Riemen, Anna H K, Clark, Susan M, De Bari, Cosimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933170/
https://www.ncbi.nlm.nih.gov/pubmed/36414376
http://dx.doi.org/10.1136/ard-2021-221682