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Methionine deficiency facilitates antitumour immunity by altering m(6)A methylation of immune checkpoint transcripts

OBJECTIVE: Methionine metabolism is involved in a myriad of cellular functions, including methylation reactions and redox maintenance. Nevertheless, it remains unclear whether methionine metabolism, RNA methylation and antitumour immunity are molecularly intertwined. DESIGN: The antitumour immunity...

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Detalles Bibliográficos
Autores principales: Li, Ting, Tan, Yue-Tao, Chen, Yan-Xing, Zheng, Xiao-Jun, Wang, Wen, Liao, Kun, Mo, Hai-Yu, Lin, Junzhong, Yang, Wei, Piao, Hai-Long, Xu, Rui-Hua, Ju, Huai-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933173/
https://www.ncbi.nlm.nih.gov/pubmed/35803704
http://dx.doi.org/10.1136/gutjnl-2022-326928