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Methionine deficiency facilitates antitumour immunity by altering m(6)A methylation of immune checkpoint transcripts
OBJECTIVE: Methionine metabolism is involved in a myriad of cellular functions, including methylation reactions and redox maintenance. Nevertheless, it remains unclear whether methionine metabolism, RNA methylation and antitumour immunity are molecularly intertwined. DESIGN: The antitumour immunity...
Autores principales: | Li, Ting, Tan, Yue-Tao, Chen, Yan-Xing, Zheng, Xiao-Jun, Wang, Wen, Liao, Kun, Mo, Hai-Yu, Lin, Junzhong, Yang, Wei, Piao, Hai-Long, Xu, Rui-Hua, Ju, Huai-Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933173/ https://www.ncbi.nlm.nih.gov/pubmed/35803704 http://dx.doi.org/10.1136/gutjnl-2022-326928 |
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