Deciphering the role of cDC2s in Sjögren’s syndrome: transcriptomic profile links altered antigen processes with IFN signature and autoimmunity

OBJECTIVE: Type 2 conventional dendritic cells (cDC2s) are key orchestrators of inflammatory responses, linking innate and adaptative immunity. Here we explored the regulation of immunological pathways in cDC2s from patients with primary Sjögren’s syndrome (pSS). METHODS: RNA sequencing of circulati...

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Detalles Bibliográficos
Autores principales: Lopes, Ana P, Hillen, Maarten R, Hinrichs, Anneline C, Blokland, Sofie LM, Bekker, Cornelis PJ, Pandit, Aridaman, Kruize, Aike A, Radstake, Timothy RDJ, van Roon, Joel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Sjögren's Syndrome
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933176/
https://www.ncbi.nlm.nih.gov/pubmed/36171070
http://dx.doi.org/10.1136/ard-2022-222728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933176/
https://www.ncbi.nlm.nih.gov/pubmed/36171070
http://dx.doi.org/10.1136/ard-2022-222728

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