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Three different pathways of IgM-antibody-dependent hemolysis are mainly regulated by complement

Antibodies to red blood cells (RBCs) may hemolyze erythrocytes via Fc-mediated phagocytosis or complement-dependent. Complement activation on RBCs can be detected by C3d-direct antiglobulin test (DAT), which is the only test in immune hematology that directly targets complement. However, a positive...

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Detalles Bibliográficos
Autores principales: Bartolmäs, Thilo, Pruß, Axel, Mayer, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933241/
https://www.ncbi.nlm.nih.gov/pubmed/36817469
http://dx.doi.org/10.3389/fimmu.2023.1114509