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Antibody Fc-chimerism and effector functions: When IgG takes advantage of IgA

Recent advances in the development of therapeutic antibodies (Abs) have greatly improved the treatment of otherwise drug-resistant cancers and autoimmune diseases. Antibody activities are mediated by both their Fab and the Fc. However, therapeutic Abs base their protective mechanisms on Fc-mediated...

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Detalles Bibliográficos
Autores principales: Cottignies-Calamarte, Andréa, Tudor, Daniela, Bomsel, Morgane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933243/
https://www.ncbi.nlm.nih.gov/pubmed/36817447
http://dx.doi.org/10.3389/fimmu.2023.1037033