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Hexokinase 2-mediated glycolysis supports inflammatory responses to Porphyromonas gingivalis in gingival fibroblasts

BACKGROUND: When infected with Porphyromonas gingivalis, gingival fibroblasts undergo metabolic reprogramming, and rely on aerobic glycolysis rather than oxidative phosphorylation for rapid energy replenishment. Hexokinases (HKs) are catalysts for glucose metabolism, and HK2 constitutes the major HK...

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Detalles Bibliográficos
Autores principales: Su, Wenqi, Li, Jingwen, Jiang, Lishan, Lei, Lang, Li, Houxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933269/
https://www.ncbi.nlm.nih.gov/pubmed/36793034
http://dx.doi.org/10.1186/s12903-023-02807-4